LDN – Low Dose Naltrexone – Prescribing Doctor Videos



Prescribing Doctor Videos



The low dose naltrexone, LDN, website is managed by volunteers in England, in particular Linda Elsegood, Trustee. All the videos are no doubt helpful, but I would point out particular interviews:


Rachel Allen, PhD – England – Dr. Allen received her PhD in Immunology from Oxford, then did work in Cambridge on the innate immune system.  She discusses the innate and adaptive immune system, glia, cytokines, and dendritic cells. This video focuses on Toll-Like Receptors which is where naltrexone acts to block pro-inflammatory cytokines that create pain. The pro-inflammatory cytokines are involved in autoimmune and other diseases.


Jarred Younger, PhD – Stanford researcher  – has published studies using LDN on persons with fibromyalgia.  He discusses plans for testing it on other conditions possibly including depression and using it for children.


Pradeep Chopra, MD – Anesthesiologist in Rhode Island – uses LDN for CRPS. With Mark Cooper, PhD, they have published two cases. The publication acknowledges my contribution in teaching them my experience. I have prescribed LDN for years in many persons with intractable pain. Prof. Cooper came to San Diego for two days November 2011, to meet and interview eight of my patients who had 100% responses with LDN for their years of intractable pain. Four responders had been able to discontinue LDN with no further recurrence of pain for years, and four remained on LDN with complete response.


Since I had no time to publish, Dr. Cooper later asked that I teach Dr. Chopra about LDN which I did over several hours. After noting in the paper that Dr. Chopra’s patient did not fully respond, I suggested to Dr. Chopra that he increase the dosage as I find not all respond to 4.5 mg. A large percentage of persons with intractable pain need higher doses. Finally, there are two populations that need lower doses than 4.5 mg but most persons with pain can be started at that dose.




The material on this site is for informational purposes only.

It is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.


Please understand that it is not legal for me

to give medical advice without a consultation.

If you wish an appointment, please telephone my office.


For My Home Page, click here:  Welcome to my Weblog on Pain Management!




One Response to “LDN – Low Dose Naltrexone – Prescribing Doctor Videos”

  1. palmitoylethanolamide4pain Says:

    Reblogged this on palmitoylethanolamide4pain and commented:
    We regularly in CRPS combine LDN (1-2.5 mg a.n.) with PeaPure and think these two therapies, with low to absent side effects, might enhance each other in inhibiting the neuro-inflammatory processes.

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