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These references include links to peer reviewed journal articles on cannabinoids. They are taken from the Reference Library of the outstanding RSD Association in Connecticut, whose mission is to help relieve pain. They have grouped the articles in helpful folders by subject, and this is one of many folders on the immense subject of pain. Please donate to them as their research helps everyone with pain, not just nerve pain or CRPS. May the references help enrich your lives and help support congress and regulators in legalizing cannabis across the country — the attorney general just now voted in by congress opposes medical marijuana.
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Be aware that states should monitor the plant for bacteria, fungus, pesticides, and heavy metals as discussed in this Smithsonian article:
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“Washington, the second state to legalize recreational marijuana, does require such testing for microbial agents like E. coli, salmonella and yeast mold, and officials there rejected about 13 percent of the marijuana products offered for sale in 2014.”
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Concentrates may be made with toxic butane or heptane. If you have cancer or are immunosuppressed – cancer and autoimmune diseases fall into that category – it is safer not to inhale. Cannabis can be used on the skin or swallowed but be aware when swallowed, it takes 60 to 90 minutes before you feel the effect. It is easy to overdose when swallowed. Check your blood pressure and pulse before use and again while you feel its effect.
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The article also points out that on testing, many of the plants have high THC but no longer have CBD, one of the 86 known cannabinoids, the one that blocks the psychoactive side effects of THC. On its own, CBD has many medical benefits.
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For those who have allodynia, the most intense form of nerve pain, pain that is triggered by a light touch or breath of air:
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Activation of cannabinoid receptor 2 attenuates mechanical allodynia and neuroinflammatory responses in a chronic post-ischemic pain model of complex regional pain syndrome type I in rats
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Keep in mind that chronic pain is much harder to treat than cancer pain and acute pain. Chronic nerve pain is the hardest of all to treat. We need to be able to prescribe anything that helps. Pain can lead to suicide in these extreme pain conditions.
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Watch out for the munchies – do not get fat.
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O’Shaunessy’s today published articles that may be useful for your Senators, healthcare insurers and states:
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“some additional articles published by cannabis clinicians in O’Shaughnessy’s showing the strength of aggregated case reports. We hope the MBC Marijuana Task Force will give them serious consideration.”
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Cannabinoids
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Title: Cannabis provides some reduction in neuropathic pain
Source: 2010-12-23 © 2010 John Wiley & Sons, Inc.
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Authors: Authors: Laura M. Borgelt, Kari L. Franson, Abraham M. Nussbaum, and George S. Wang
Title: The Pharmacologic and Clinical Effects of Medical Cannabis
Source: PHARMACOTHERAPY Volume 33, Number 2, 2013
Source: Canadian Family Physician • Le Médecin de famille canadien | Vol 61: august • août 2015
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Authors: Amol Deshpande MD MBA, Angela Mailis-Gagnon MSc MD FRCPC, Nivan Zoheiry MD PhD, Shehnaz Fatima Lakha
Title: Efficacy and adverse effects of medical marijuana for chronic noncancer pain Systematic review of randomized controlled trials
Source: Canadian Family Physician • Le Médecin de famille canadien | Vol 61: august • août 2015
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Authors: Bjorn Jensen, Jeffrey Chen, Tim Furnish, Mark Wallace
Title: Medical Marijuana and Chronic pain: A Review of Basic Science and Clinical Evidence
Source: Curr Pain Headache Rep (2015) 19:50 DOI 10.1007/s11916-015-0524-x
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Author: Kevin P. Hill, MD, MHS
Title: Medical Marijuana for Treatment of Chronic Pain and Other Medical and Psychiatric Problems A Clinical Review
Source: JAMA June 23/30, 2015 Volume 313, Number 245
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Authors: Mary E. Lynch, Fiona Campbell
Title: Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials
Source: DOI:10.1111/j.1365-2125.2011.03970.x
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Author: Grace Thomas, MD, Robert A. Kloner, MD, and Shereif Rezkalla, MD
Title: Adverse Cardiovascular, Cerebrovascular, and Peripheral Vascular Effects of Marijuana Inhalation: What Cardiologists Need to Know
Source: The American Journal of Cardiology (www.ajconline.org)
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Author: Jijun Xu, Yuying Tang, Mian Xie, Bihua Bie, Jiang Wu, Hui Yang, Joseph F. Foss, Bin Yang, Richard W. Rosenquist, and Mohamed Naguib
Title: Activation of cannabinoid receptor 2 attenuates mechanical allodynia and neuroinflammatory responses in a chronic post-ischemic pain model of complex regional pain syndrome type I in rats
Source: European Journal of Neuroscience, pp. 1-10, 2016 doi:10.1111/ejn.13414
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